Biochemical Parameters in Patient of Sickle Cell Anaemia in Malwaregion - A Case Report

Authors

  • H. Bawariya Department of Biochemistry, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh. Author
  • D. Jain Department of Biochemistry, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh. Author
  • M. Paliwal Department of Biochemistry, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh. Author
  • R.C. Thanna Department of Biochemistry, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh. Author
  • N. Sharma Department of Biochemistry, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh. Author
  • R. Shetty Department of Biochemistry, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh. Author

Keywords:

Sickle cell anaemia (SCA), Biochemical parameters, Malwa region

Abstract

Sickle cell anaemia (SCA) is a hereditary hemoglobinopathy characterized by chronic haemolytic anaemia, Vaso-occlusive crises, and multi organ involvement. Biochemical alterations associated with SCA provide insight into disease severity, haemolytic activity, hepatic and renal status, and oxidative stress. This case report describes the biochemical profile like sodium, creatinine, LFT, iron and ferritin of a diagnosed sickle cell anaemia patient from the Malwa region of Madhya Pradesh, India, highlighting characteristic laboratory changes and their clinical relevance. The importance of routine biochemical monitoring in Sickle cell anaemia patient for early detection of complications.

References

1. Banerje e S, Owen C, Chopra S. Sickle cell hepatopathy. Hepatology 2001;33:1021-8.

2. Hassell KL, Eckman JR, Lane PA. Acute multiorgan failure syndrome: A potentially catastrophic complication of severe sickle cell pain episodes. Am J Med 1994;96:155-62.

3. Meshikhes AW, al-Faraj AA. Sickle cell disease and the general surgeon. J R Coll Surg Edinb 1998;43:73-9.

4. Kotila T, Adedapo K, Adedapo A, Oluwasola O, Fakunle E, Brown B. Liver dysfunction in steady state sickle cell disease. Ann Hepatol 2005;4:261-.

5. Kar, B. C. (1991). Sickle cell disease in India. Journal of Association of Physician of India, 39: 954-960.

6. Allon M. Renal abnormalities in sickle cell disease. Arch Intern Med. 1990;150(3):501–504. doi: 10.1001/archinte. 1990.00390150015003. [PubMed] [CrossRef] [Google Scholar]

7. Pandey S, Sharma A, Dahia S, Shah V, Sharma V, Mishra RM, Pandey S, Saxena R. Biochemical indicator of sickle cell disease: preliminary report from India. Indian J Clin Biochem. 2012 Apr;27(2):191-5. doi: 10.1007/s12291-0110162-y. Epub 2011 Sep 25. PMID: 23542695; PMCID: PMC3358379

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Published

2026-07-24

How to Cite

Biochemical Parameters in Patient of Sickle Cell Anaemia in Malwaregion - A Case Report. (2026). MP Journal of Medical Sciences, 1(1), 66-68. https://mpjms.com/index.php/mpjms/article/view/16